Module: Lysis

For large DNA phages, host cell lysis is an active genetically programmed pathway that releases phages from the infected cell into the environment. Lysis is independent of virion assembly and involves targeted disruption of the cell envelope layers.

o-spanin Description:

Outer membrane subunit of the two-component spanin system. The maturation of the o-spanin includes posttranslational modification by lipoylation. The o-spanin is involved in outer membrane disruption during host cell lysis by phage.

Protein Function

o-spanin

paired bimolecular spanin: putative i-spanin

spanin type: EMBEDDED